Porous ceramics and glasses for biomedical applications
Implantable biomaterials are often designed in the form of porous templates to allow tissue regeneration, ingrowth and remodeling in 3D. This activity focuses on the production and characterization of ceramics, glasses and composites with different scales of porosity (from macro- to nano-range), including hierarchical biomaterials and hybrids. Applications are mainly addressed to the development of scaffolds for bone tissue engineering and ocular devices (orbital implants), as well as advanced therapy of bone cancer by hyperthermia. Production methods include foaming strategies, sol-gel process and relevant combinations. The use of sustainable templates for scaffolding was also considered, for example in the frame of a collaboration with the Turin Polytechnic University in Tashkent (Uzbekistan). Additive manufacturing technologies are used to fabricate porous bioceramics and glasses In the frame of collaborations with Tampere University (Finland) and the company Lithoz (Austria).
Relevant publications:
Baino F., Fiume E., Miola M., Leone F., Onida B., Verné E. Fe-doped bioactive glass-derived scaffolds produced by sol-gel foaming, Mater Lett, vol. 235, pp. 207-211, 2019. http://hdl.handle.net/11583/2721503
Fiume E., Serino G., Bignardi C., Verné E., Baino F. Bread-derived bioactive porous scaffolds: an innovative and sustainable approach to bone tissue engineering, Molecules, vol. 24, id. 2954, 2019. http://hdl.handle.net/11583/2766335
Baino F., Fiume E., Barberi J., Kargozar S., Marchi J., Massera J., Verné E. Processing methods for making porous bioactive glass‐based scaffolds – A state-of-the-art review, Int J Appl Ceram Technol, vol. 16, pp. 1762-1796, 2019. http://hdl.handle.net/11583/2766415
Baino F., Verné E., Fiume E., Peitl O., Zanotto E.D., Brandao S.M., Schellini S.A. Bioactive glass and glass‐ceramic orbital implants, Int J Appl Ceram Technol, vol. 16, pp. 1850-1863, 2019. http://hdl.handle.net/11583/2766417
Barberi J., Baino F., Fiume E., Orlygsson G., Nommeots-Nomm A., Massera J., Verné E. Robocasting of SiO2-based bioactive glass scaffolds with porosity gradient for bone regeneration and potential load-bearing applications, Materials, vol. 12, id. 2691, 2019. http://hdl.handle.net/11583/2766336