Electronic diary for Parkinson’s disease

The "electronic diary" has the aim of estimating the patient's motor status by means of low-cost, wearable sensors. Clinically, this will allow a better calibration of the drug dosage on each single patient. A first phase addresses experimentation in a controlled environment, the second one in a domestic environment, with appropriate interfaces to the hospital where the data can be consulted by clinicians.

The use of smartphones and artificial intelligence algorithms is analysed to estimate quantities such as leg agility, freezing of gait, postural transitions, postural stability (the same features measured by the neurologist during the visit). Advanced research will address early markers of evolution, development of dyskinesia / orthostatic hypotension / risk of falls, response to drugs or to the deep brain stimulation, study of atypical cases, study of sleep disturbances, and participation in large-scale trials.

Pubblicazioni attinenti:

Borzì L., Varrecchia M., Olmo G., Artusi C.A., Fabbri M., Rizzone M.G., Romagnolo A., Zibetti M., Lopiano L. Home monitoring of motor fluctuations in Parkinson’s disease patients, J Rel Intell Environm, vol. 5,  pp.145–162, 2019. hdl:11583/2741833